I have a main PC driving two x 27" monitors via a KVM switch which also has a feed from my laptop docking station.
Lenovo wired keyboard - for the positive key action, and an ergonomic logitech mouse big enough to not give you carpal tunnel.
I think if I was starting out again - I would still go for twin monitors but the big change would be to go for a full electrically-height-adjustable desk to allow work standing up.
Alternating between sitting and standing when you are at the computer for long periods is so good for posture.