These are both good makes so you probably won't go too far wrong. The frame geometries are different so that may well make a difference to the feel on the road. I had a quick look and the components look a bit better on the Cannondale but they are a mix.
I suggest you try and ride each one if you can?
My other thoughts are to find a local shop (with a sale) and maybe buy from them if they can give you a good deal as they can size it properly etc.
Just my 2p worth...
A